病理学与病理生理学 遗传学 博士生导师

陕西省青年科技新星

陕西省三秦人才

中国实验动物学会优秀青年人才

西安交通大学优秀博士后

陕西省实验动物学会  副会长

曾在美国斯坦福大学和日本山梨大学做访问学者，在国内外杂志发表论文100余篇，其中SCI收录70余篇。获得陕西省高等学校科技进步奖1项(第1完成人)，中国实验动物学会优秀青年人才奖1项，中国实验动物学会科学技术三等奖1项(第1完成人)，中国实验动物学会科学技术二等奖2项(第2完成人)。陕西省科技进步二等奖1项(第5完成人)。主持国家自然科学基金2项，陕西省科技项目3项，中央高校基本科研业务费专项资金-青年教师跟踪支持项目(优青培育类)1项，博士后基金2项(其中特别资助1项)，西安交通大学基金3项，参与863项目、国家自然科学基金和陕西省重大科技项目多项，担任多个国内外期刊编委。 

近年代表论文（*通讯作者）：

1. Liu H, Tian K, Fu W, Qin L, Tian R, Wei P, Zou J, Alam N, Malik F, Li K, Li M, Xu B, Guo J, Xia C, Wang R, Wang W, Bai L, Liu E, Xu B, Li Y*, Zhao S*. Tranilast ameliorates experimental abdominal aortic aneurysm by inhibiting the NLRP3 inflammasome pathway. J Pharm Anal. 2026 Mar;16(3):101453.

2. Liu H, Qin L, Zou J, Tian K, Li K, Tian R, Malik F, Wei P, Xia C, Hou H, Cai T, Meng Y, Liu E, Xu B, Zhao S*. Intra-aortic infusion of nicotine can induce a novel mouse model of abdominal aortic aneurysm. Eur J Pharm Sci. 2025 Aug 1;211:107143.

3. Tian K, Tian R, Qin L, Liu H, Malik F, Wei P, Zou J, Li K, Hou H, Sun K, Wang R, Wang W, Bai L, Xu B, Liu E and Zhao S*. Animal studies and AI-based analysis identify the efficacy of berberine to inhibit experimental abdominal aortic aneurysms. Phytomedicine. 2025;147:157176.

4. Wei P, Tian K, Liu H, Li K, Alam N, Cheng D, Li M, He X, Guo J, Wang R, Wang W, Bai L, Liu E, Xu B, Li Y, Zhao S*. Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167170.

5. Fu Y, Liu H, Li K, Wei P, Naqash Alam, Deng J, Li M, Wu H, He X, Hou H, Xia C, Wang R, Wang W, Bai L, Xu B, Li Y, Wu Y, Liu E* and Zhao S*. C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms. Front Immunol. 2023,14:1233807.

6. Liu H, Zhang J, Xue Z, Chang M, Feng X, Cai Y, Bai L, Wang W, Liu E, Zhao S*, Wang R*. Deficiency of protein inhibitor of activated STAT3 exacerbates atherosclerosis by modulating VSMC phenotypic switching. Atherosclerosis. 2023;380:117195.

7. Yu Q, Wei P, Xu L, Xia C, Li Y, Liu H, Song X, Tian K, Fu W, Wang R, Wang W, Bai L, Fan J, Liu E and Zhao S*. Urotensin II enhances advanced aortic atherosclerosis for-mation and delays plaque regression in hyperlipidemic rabbits. Int J Mol Sci. 2023, 24(4), 3819.

8. Tian K#, Xia C#, Liu H, Xu B, Wei P, Fu W, Lu M, Li Y, Li Y, Cheng D, Liu E, Zhao S*. Temporal and Quantitative Analysis of Aortic Immunopathologies in Elastase-Induced Mouse Abdominal Aortic Aneurysms. J Immunol Res. 2021:6297332.

9. Yu Q#, Cheng D#, Xu L, Li Y, Zheng X, Liu Y, Li Y, Liu H, Bai L, Wang R, Fan J, Liu E*, Zhao S*. Urotensin II and urantide exert opposite effects on the cellular components of atherosclerotic plaque in hypercholesterolemic rabbits. Acta Pharmacol Sin. 2020, 41(4): 546-553. (#共同第一作者；*通讯作者)

10. Bai L#, Liu B#, Ji C#, Zhao S#, Liu S, Wang R, Wang W, Yao P, Li X, Fu X, Yu H, Liu M, Han F, Guan N, Liu H, Liu D, Tao Y, Wang Z, Yan S, Florant G, Butcher MT, Zhang J, Zheng H, Fan J, Enqi Liu. Hypoxic and Cold Adaptation Insights from the Himalayan Marmot Genome. iScience. 2019;11:519-530. ( #共同第一作者)

邮箱：sihaizhao@xjtu.edu.cn

电话：029-82655361

个人主页：https://gr.xjtu.edu.cn/en/web/sihaizhao